Liver fluke is known to cause severe clinical disease and death, costing the sheep industry alone millions of pounds every year. Now spreading to new regions liver fluke can increasingly be found throughout the UK, largely due to the impact of climate change. All these factors favour liver fluke:
Due to this lengthening of seasons, and the impact of warm, wet weather on the liver fluke lifecycle, the liver fluke challenge can now be higher for a longer period with the risk of high fluke burdens in both sheep and cattle extending throughout the year if not treated effectively.
Resistance to certain active ingredients has been identified on a number of farms. Once liver fluke have become resistant to an active ingredient, and can survive exposure to a treatment that would normally kill them, there is no evidence to suggest they will return to susceptibility. As individuals, and as an industry, we can’t afford to allow this to happen. To achieve effective control now – and to preserve the efficacy of the existing active ingredients for the future – we need to adopt a new approach to liver fluke management. 4 elements of sustainable liver fluke control:
Controlling the right stage of liver fluke at the right time is important for sustainable liver fluke control; Fasinex 5% kills every stage in one easy-to-use dose. Fasinex 5% contains triclabendazole, the only active proven to kill all three stages of liver fluke: acute (early immature), sub-acute (immature) and chronic fluke disease (adult). Requiring fewer doses to achieve the same fluke kill as other flukicides.
Controlling the right stages of liver fluke at the right time is vital for effective liver fluke control. When looking for a combined liver flukicide and wormer, Fasimec Duo is the product of choice. Combining ivermectin and triclabenzadole in a combined wormer and flukicide, Fasimec Duo controls all significant gastrointestinal roundworms and lung worms in one easy-to-use drench. Fasimec Duo kills all three stages of liver fluke – early immature, immature and adult – down to less than one week of age and has a short meat withdrawal of just 27 days.
Combinex for sheep is an effective liver flukicide and wormer. Combining the active ingredient, triclabendazole, which kills all stages of fluke, alongside a broad spectrum levamisole wormer, Combinex is an easy-to-use drench. Triclabendazole is the only active ingredient that kills all three stages of liver fluke (Fasciola hepatica), while levamazole provides worm control for roundworms. Combinex treats and controls parasitic bronchitis, parasitic gastroenteritis and fasciolosis.
Controlling the right stage of fluke at the right time is essential for the health and wellbeing of sheep. Immature and adult liver fluke present themselves in winter and early spring – use Flukiver for effective treatment.
Flukiver is a flukicide for the control of adult and immature liver fluke, Haemonchus contortus (barbers pole worm) and nasal bots in sheep and lambs. It can be used on farms with triclabendazole resistance, and also prevents contamination of pastures with fluke eggs for 13 weeks1. Flukiver is effective against benzimidazole resistant strains of Haemonchus contortus.
Superverm is the ideal treatment of immature and adult liver fluke, while providing effective protection against a wide range of intestinal worms and lungworm in sheep. The combination of closantel and mebendazole in Supaverm protects sheep against liver fluke and worms (lungworm, roundworm and tapeworm) in one easy-to-administer oral drench. It controls chronic (adult) and subacute (immature) fascioliasis (due to Fasciola hepatica) in sheep and lambs, whilst reducing the number of eggs passing onto the pasture and helping combat pasture contamination.
Fasinex® 5% Oral Suspension for sheep contains 5% (w/v) triclabendazole and is indicated for the treatment and control of liver fluke infections in sheep caused by all stages of triclabendazole susceptible Fasciola hepatica from 2 day old immature to adult fluke.
Fasimec® Duo Oral Suspension for sheep contains 0.1% (w/v) ivermectin and 5% (w/v) triclabendazole and is indicated for the treatment of mixed trematode (fluke) and nematode or arthropod infections due to gastrointestinal roundworms, lungworms, liver fluke and nasal bots.
Combinex® Oral Suspension for sheep contains 3.75% (w/v) levamisole hydrochloride and 5% (w/v) triclabendazole and is indicated For the treatment and control of parasitic bronchitis, parasitic gastro-enteritis and fascioliasis in sheep. When used at the recommended dose rate, the product is effective against mature and developing immature stages of levamisole-susceptible Haemonchus, Ostertagia, Trichostrongylus, Cooperia, Nematodirus, Bunostomum, Chabertia and Oesophagostomum species in the gastro-intestinal tract, and Dictyocaulus spp in the lungs. It is also effective against all stages of Triclabendazole susceptible Fasciola hepatica from two day old early immature to adult fluke, and so is indicated against both acute and chronic fascioliasis.
Flukiver® 5% w/v Oral Suspension contains 50mg/ml closantel and is indicated for the control of chronic and subacute fascioliasis (due to Fasciola hepatica) in sheep and lambs. For the control of Oestrus ovis (Sheep Nasal Bot Fly). For the control of inhibited, immature and adult stages of Haemonchus contortus (Barber Pole Worm) including benzimidazole resistant strains. Flukiver is active against mature and immature flukes.
Supaverm® Oral Suspension contains 5% w/v closantel and 7.5% w/v mebendazole and is indicated for the control of fascioliasis (due to Fasciola hepatica) and gastrointestinal nematodes and cestodes in sheep and lambs. The combination is active against lungworm, roundworms, tapeworms (heads and segments) and fluke (mature and immature). The control of the larval stages of Oestrus ovis (Sheep Nasal Bot fly), and the control of inhibited, immature and adult stages of Haemonchus contortus (Barber Pole worm) including benzimidazole resistant strains.
Legal category for all: POM-VPS.
Information regarding the side effects, precautions, warnings and contra-indications can be found in product packaging and leaflets; further information can also be found in the Summary of Product Characteristics.
For further information call Elanco Animal Health on 01256 353131 or write to Elanco Animal Health (the animal health division of Eli Lilly and Company Limited), Lilly House, Priestley Road, Basingstoke, Hampshire, RG24 9NL.
Elanco™, Fasinex® 5%, Fasimec® Duo, Combinex®, Flukiver® 5%, Supaverm® and the Diagonal Bar™ are trademarks owned by or licensed to Eli Lilly and Company, its affiliates or subsidiaries. Use medicines responsibly (www.noah.co.uk/responsible). Advice should be sought from the prescriber prior to use.